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KMID : 0952820160190010001
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Journal of Korean Cleft Lip & Palate Association
2016 Volume.19 No. 1 p.1 ~ p.10
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Orthodontic Treatment in a Patient with Chromosome
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Son Woo-Sung
Noh Tae-Kyung
Kim Sung-Hun
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Abstract
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Chromosome 18p deletion syndrome or 18p- syndrome is a genetic condition caused by a deletion of genetic materials within chromosome 18, and the deletion involves the short arm of chromosome 18. It causes a wide range of medical and developmental concerns, such as mental retardation, short stature, holoprosencephaly, ptosis, small mandible, excessive caries, and dental anomalies. At present, the treatment for 18q- syndrome is only symptomatic. This article presents a case report: orthodontic treatment of a 14-year-old male patient with 18p- syndrome. He has a mental retardation, anomalous maxillary central incisor and small mandible. Due to macrodontia in maxilla and small mandible, there was a severe crowding. We proceeded with the extraction of upper and lower first premolars and a good alignment of teeth was obtained. But, because of mental retardation, the orthodontic treatment had a limitation. The special considerations of orthodontic treatment for the patient with 18p- syndrome are discussed.
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KEYWORD
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18p deletion syndrome, genetic disorder, orthodontic treatment
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